SuperSonic Picture: Prediction of Survival in Sufferers with Chronic Liver Illness: a Study Confirms the Clinical Advantage of ShearWave Elastography

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AIX-EN-PROVENCE, France–(Company WIRE)–Regulatory News:

SuperSonic Picture (Paris:SSI) (Euronext: SSI, FR0010526814), a firm specializing in healthcare imaging utilizing ultrasound technologies, announces that a multicenter retrospective study performed in Europe and China, has confirmed the clinical utility of ShearWave&#x2122 Elastography in individuals with chronic liver illness, the 1st outcomes1 of which had been presented at the International Liver Congress (ILC 2019). The objective of this study was to evaluate the diagnostic worth of ShearWave Elastography (SWE) in the progression of chronic liver illness and in the improvement of connected complications. SWEtwo is an revolutionary imaging mode created by SuperSonic Picture, which enables the visualization and measurement of tissue elasticity.

“Since its creation, SuperSonic Picture has been supplying physicians with new innovations that have changed the paradigm of ultrasound practice, becoming the normal in pathways of non-invasive care. Recognizing the higher diagnostic worth of its biomarker in the prediction of survival, SuperSonic Picture has taken a new step towards earlier and far better-adapted patient management. This study not only confirms the knowledge of SuperSonic Picture in the evaluation of liver illness, but also the diagnostic added benefits of its ultrasound innovations. To date, more than 160 clinical articles have been published on the use of ShearWave Elastography in individuals with liver illness,” concludes Michèle Lesieur, CEO of SuperSonic Picture.

The clinical worth of ShearWaveTM Elastography for the prognostic evaluation of individuals with chronic liver illness

The measurement of hepatic elasticity, displayed in kilopascals (kPa), is a effectively-established strategy for assessing the severity of fibrosis in individuals with chronic liver illnesses. This criterion has come to be an critical parameter for figuring out the degree of progression of the illness. Nonetheless, the worth of shear-wave primarily based elastography for predicting mortality in cirrhotic individuals has hitherto remained undetermined.

As a hepatologist, I can say that the quantity of individuals with chronic liver illness is continually growing, and that it really is becoming ever a lot more essential for physicians, radiologists and hepatologists, to have trustworthy tools such as SWE to address this important public wellness challenge in the most efficient way. This study has permitted us to establish a new threshold worth to enable predict outcomes for every single patient. Sufferers reaching a lot more than 20.six kPa are at two-fold greater threat of death inside one particular year. This is critical for the reason that it can be applied as a biomarker to stratify care in individuals with cirrhosis,” explains Professor Jonel Trebicka, University Clinic of Frankfurt, Germany.

The study performed in 15 centers in Europe and China integrated 1434 individuals with a median age of 55 years, 58% of whom had been guys. Inclusion criteria had been the presence of chronic liver illness with a SWE measurement at the onset of the illness, no preceding decompensation occasion, and at least one particular year of clinical adhere to-up soon after the SWE measurement (median adhere to-up 34.eight months).

About a year ago, SuperSonic Picture released its new Aixplorer MACH® 30 Hepato that integrates the complete variety of imaging modes and is believed to represent the market normal in hepatology with its elastography ShearWave PLUS, which enables true-time visualization and measurement of tissue stiffness. The Aixplorer MACH 30 also delivers ‘B-mode Ratio’ for detecting intrahepatic steatosis, Angio PL.U.S. to supply unparalleled resolution for the imaging of microvascularisation of lesions, and also Doppler and contrast imaging, for the screening and characterization of liver nodules. Liver applications stay strategic for SuperSonic Picture and with its new generation of UltraFast&#x2122 imaging introduced on the Aixplorer MACH 30, the firm is continuing its improvement of new ultrasound markers for the liver.

In addition, the outcomes of other multicenter research published in many prestigious journals, such as Gastroenterology, Radiology, Hepatology and GUT, have also confirmed the superiority of the diagnostic functionality of ShearWave Elastography for the non-invasive evaluation of liver fibrosis. For a lot more data, please seek the advice of our press release of 24 September 2018.

About SuperSonic Picture

SuperSonic Picture specializes in ultrasound healthcare imaging. The firm manufactures the flagship Aixplorer® series of merchandise, which function the company’s exclusive UltraFast&#x2122 technologies. UltraFast&#x2122 has provided rise to new imaging modes that set the requirements of care for non-invasive characterization of breast, liver and prostate illnesses. The 1st groundbreaking UltraFast&#x2122 mode created is ShearWave&#x2122 Elastography (SWE&#x2122), which enables physicians to view and instantaneously analyze tissue stiffness, a vitally critical issue in the diagnosis of quite a few circumstances. To date, a lot more than 600 published articles have validated the diagnostic worth of SWE. The most current addition to the Aixplorer® variety is the Aixplorer MACH® 30 ultrasound platform that introduces the subsequent generation of UltraFast&#x2122 imaging, which optimizes the system’s revolutionary imaging modes: ShearWave PLUS, Doppler UltraFast&#x2122, Angio PL.U.S, TriVu and Needle PL.U.S. The firm has a lot more than two,300 ultrasound systems installed in more than 80 nations. Its most important development markets are China, the United States and the European Union (France). In 2018, the firm generated a turnover of €24.six million in 2018. SuperSonic Picture is a firm listed on Euronext (symbol: SSI).

For a lot more data, check out www.supersonicimagine.com.

1 https://www.postersessiononline.eu/173580348_eu/congresos/ILC2019/aula/-SAT_133_ILC2019.pdf

two Obtainable only on Aixplorer® ultrasound systems.

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