Longxiang Xie,1 Qiang Wang,1 Fangmei Nan,1 Linna Ge,1 Yifang Dang,1 Xiaoxiao Sun,1 Ning Li,1 Huan Dong,1 Yali Han,1 Guosen Zhang,1 Wan Zhu,two Xiangqian Guo1
1Bioinformatics Division of Predictive Medicine, Institute of Biomedical Informatics, Cell Signal Transduction Laboratory, Bioinformatics Center, Henan Provincial Engineering Center for Tumor Molecular Medicine, College of Application, College of Fundamental Health-related Sciences, Henan University, Kaifeng 475004, People’s Republic of China twoDivision of Anesthesia, Stanford University, Stanford, CA, USA
Correspondence: Xiangqian Guo
Bioinformatics Division of Predictive Medicine, Institute of Biomedical Informatics, Cell Signal Transduction Laboratory, Bioinformatics Center, Henan Provincial Engineering Center for Tumor Molecular Medicine, College of Application, College of Fundamental Health-related Sciences, Henan University, Kaifeng 475004, People’s Republic of China
E-mail [email protected]
Abstract: Gene expression profiling information with lengthy-term clinical adhere to-up facts are wonderful sources to screen, create, evaluate and validate prognostic biomarkers in translational cancer analysis. Even so, an quick-to-use interactive on the net tool is necessary to analyze these profiling and clinical information. In the present operate, we created OSacc (On line consensus Survival evaluation of ACC), a net tool that offers speedy and user-friendly survival evaluation primarily based on seven independent transcriptomic profiles with lengthy-term clinical adhere to-up facts of 259 ACC sufferers gathered from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) databases. OSacc enables researchers and clinicians to evaluate the prognostic worth of genes of interest by Kaplan–Meier (KM) survival plot with hazard ratio (HR) and log-rank test in ACC. OSacc is freely readily available at http://bioinfo.henu.edu.cn/ACC/ACCList.jsp.
Keywords and phrases: ACC, prognostic marker, more than survival, net tool, KM plot
This operate is published and licensed by Dove Health-related Press Restricted. The complete terms of this license are readily available at https://www.dovepress.com/terms.php and incorporate the Inventive Commons Attribution – Non Industrial (unported, v3.) License.
By accessing the operate you hereby accept the Terms. Non-industrial makes use of of the operate are permitted with out any additional permission from Dove Health-related Press Restricted, offered the operate is effectively attributed. For permission for industrial use of this operate, please see paragraphs four.two and five of our Terms.